Proteomics and Cell Biology

Proteomics

Being integrated into the Proteomics and Mass Spectrometry Core Facility, our research focuses on the study of system-wide protein regulation using (mostly, but not exclusively) mass spectrometry based technology. We have developed a LC-MS/MS based method for the characterization of circulating microparticles in human plasma. The idea is to offer a comprehensive diagnostic method in order to study these particles in medical research of cardiovascular and pneumological diseases. Our laboratory is furthermore equipped with a cone-and-plate apparatus setup on which adherent cells, e.g. endothelial cells, can be subjected to well-defined shear stress of different quality. The idea is to study in-vitro the molecular processes of endothelial cell biology (arteriogenesis, angiogenesis) under shear stress.


 

Contact

Heller Manfred, PD Dr. phil. nat., Group leader

KiKl D841
Inselspital 
3010 Bern
Email: manfred.heller@dkf.unibe.ch
Phone  +41 31 632 84 04
Fax       +41 31 632 84 99

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