Cardiovascular Research Cluster Bern

2021

Publications 2021 

Neugebauer F, Noti F, van Gool S, Roten L, Baldinger SH, Seiler J, Madaffari A, Servatius H, Ryser A, Tanner H, Reichlin T, Haeberlin A. Leadless atrioventricular synchronous pacing in an outpatient setting: Early lessons learned on factors affecting atrioventricular synchrony. Heart Rhythm. 2021 Dec 29:S1547-5271(21)02517-0. https://doi.org/10.1016/j.hrthm.2021.12.025

Servatius H, Küffer T, Baldinger SH, Asatryan B, Seiler J, Tanner H, Novak J, Lam A, Noti F, Haeberlin A, Madaffari A, Sweda R, Mühl A, Branca M, Dütschler S, Erdoes G, Stüber F, Theiler L, Reichlin T, Roten L. Dexmedetomidine versus propofol for operator-directed nurse-administered procedural sedation during catheter ablation of atrial fibrillation: A randomized controlled study. Heart Rhythm. 2021 Dec 28:S1547-5271(21)02520-0. https://doi.org/10.1016/j.hrthm.2021.12.028

Guo X, Franco OH, Laine JE. Accelerated ageing in the COVID-19 pandemic: A dilemma for healthy ageing. Maturitas. 2021 Dec 27;S0378-5122(21)00352-2. https://doi.org/10.1016/j.maturitas.2021.12.009

Okuno T, Tomii D, Heg D, Lanz J, Praz F, Stortecky S, Reineke D, Windecker S, Pilgrim T. Five-year outcomes of mild paravalvular regurgitation after transcatheter aortic valve implantation. EuroIntervention. 2021 Dec 22;EIJ-D-21-00784. doi: 10.4244/EIJ-D-21-00784

Brusa J, Lutz E, Schönhoff F, Weiss S, Schmidli J, Makaloski V. One-year outcome of postoperative stroke and nerve injury after supraclavicular revascularization of the left subclavian artery for proximal landing zone extension in thoracic endovascular aortic repair. Ann Vasc Surg. 2021 Dec 22;S0890-5096(21)00964-X. https://doi.org/10.1016/j.avsg.2021.12.009

Fischer K, Linder OL, Erne SA, Stark AW, Obrist SJ, Bernhard B, Guensch DP, Huber AT, Kwong RY, Gräni C. Reproducibility and its confounders of CMR feature tracking myocardial strain analysis in patients with suspected myocarditis. Eur Radiol. 2021 Dec 21; https://doi.org/10.1007/s00330-021-08416-5

Fudim M, Wojdyla DM, Alexander JH, Goodman SG, Mehran R, Windecker S, Aronson R, Vinereanu D, Halvorsen S, Bahit MC, Granger CB, Lopes RD. Efficacy and Safety of Antithrombotic Therapy in Patients With Atrial Fibrillation, Recent Acute Coronary Syndrome, or Percutaneous Coronary Intervention and a History of Heart Failure: Insights From the AUGUSTUS Trial. J Am Heart Assoc. 2021 Dec 21;10(24):e023143. https://doi.org/10.1161/JAHA.121.023143

Grisotto G, Farago JS, Taneri PE, Wehrli F, Roa-Díaz ZM, Minder B, Glisic M, Gonzalez-Jaramillo V, Voortman T, Marques-Vidal P, Franco OH, Muka T. Dietary factors and onset of natural menopause: a systematic review and meta-analysis. Maturitas, 2021 Dec 21, 159:15-32. https://doi.org/10.1016/j.maturitas.2021.12.008

Greutmann M, Ruperti J, Schwitz F, Haag N, Santos Lopes B, Meier L, Babic D, Valsangiacomo Buechel E, Kellenberger C, Bonassin F, Attenhofer Jost C, Schwerzmann M, Wustmann K, Tobler D. High Variability of Right Ventricular Volumes and Function in Adults with Severe Pulmonary Regurgitation Late After Tetralogy of Fallot Repair. Am J Cardiol. 2021 Dec 20;S0002-9149(21)01150-4. https://doi.org/10.1016/j.amjcard.2021.11.022

Allard L, Bernhard B, Windecker S, Valgimigli M, Gräni C. Left ventricular thrombus in ischaemic heart disease: diagnosis, treatment and gaps of knowledge. Eur Heart J Qual Care Clin Outcomes. 2021 Dec 20;qcab097. https://doi.org/10.1093/ehjqcco/qcab097

Levis A, Egli N, Jenni H, Hautz WE, Daley JI, Haenggi M. Use of a disposable vascular pressure device to guide balloon inflation of resuscitative endovascular balloon occlusion of the aorta: a bench study. Sci Rep. 2021 Dec 15;11(1):24055. https://doi.org/10.1038/s41598-021-03502-6

Koell B, Orban M, Weimann J, Kassar M, Karam N, Neuss M, Petrescu A, Iliadis C, Unterhuber M, Adamo M, Giannini C, Melica B, Ludwig S, Massberg S, Praz F, Pfister R, Thiele H, Stephan von Bardeleben R, Baldus S, Butter C, Lurz P, Windecker S, Metra M, Petronio AS, Hausleiter J, Lubos E, Kalbacher D; EuroSMR Investigators. Outcomes Stratified by Adapted Inclusion Criteria After Mitral Edge-to-Edge Repair. J Am Coll Cardiol. 2021 Dec 14;78(24):2408-2421. https://doi.org/10.1016/j.jacc.2021.10.011

Koppe-Schmeißer F, Schwaderlapp M, Schmeißer J, Dopheide JF, Münzel T, Daiber A, Espinola-Klein C. Influence of Peripheral Transluminal Angioplasty Alongside Exercise Training on Oxidative Stress and Inflammation in Patients with Peripheral Arterial Disease. J Clin Med. 2021 Dec 13;10(24):5851. https://doi.org/10.3390/jcm10245851

Gonzalez-Jaramillo N, Marcin T, Matter S, Eser P, Berlin C, Bano A, Heg D, Franco OH, Windecker S, Räber L, Wilhelm M. Clinical outcomes and cardiac rehabilitation in underrepresented groups after percutaneous coronary intervention: an observational study. Eur J Prev Cardiol. 2021 Dec 11:zwab204. https://doi.org/10.1093/eurjpc/zwab204

Panagides V, Del Val D, Abdel-Wahab M, Mangner N, Durand E, Ihlemann N, Urena M, Pellegrini C, Giannini F, Gasior T, Wojakowski W, Landt M, Auffret V, Sinning JM, Cheema AN, Nombela-Franco L, Chamandi C, Campelo-Parada F, Munoz-Garcia E, Herrmann HC, Testa L, Won-Keun K, Castillo JC, Alperi A, Tchetche D, Bartorelli AL, Kapadia S, Stortecky S, Amat-Santos I, Wijeysundera HC, Lisko J, Gutiérrez-Ibanes E, Serra V, Salido L, Alkhodair A, Livi U, Chakravarty T, Lerakis S, Vilalta V, Regueiro A, Romaguera R, Kappert U, Barbanti M, Masson JB, Maes F, Fiorina C, Miceli A, Kodali S, Ribeiro HB, Mangione JA, Sandoli de Brito F Jr, Actis Dato GM, Rosato F, Ferreira MC, Correia de Lima V, Colafranceschi AS, Abizaid A, Marino MA, Esteves V, Andrea J, Godinho RR, Alfonso F, Eltchaninoff H, Søndergaard L, Himbert D, Husser O, Latib A, Le Breton H, Servoz C, Pascual I, Siddiqui S, Olivares P, Hernandez-Antolin R, Webb JG, Sponga S, Makkar R, Kini AS, Boukhris M, Gervais P, Linke A, Crusius L, Holzhey D, Rodés-Cabau J. Perivalvular Extension of Infective Endocarditis after Transcatheter Aortic Valve Replacement. Clin Infect Dis. 2021 Dec 11:ciab1004. https://doi.org/10.1093/cid/ciab1004

Alijla F, Buttia C, Reichlin T, Razvi S, Minder B, Wilhelm M, Muka T, Franco OH, Bano A. Association of diabetes with atrial fibrillation types: a systematic review and meta-analysis. Cardiovasc Diabetol. 2021 Dec 7;20(1):230. https://doi.org/10.1186/s12933-021-01423-2

Bartkowiak J, Reineke D, Tomii D, Brugger N, Pilgrim T, Terbeck S, Khan JM, Windecker S, Lanz J, Praz F. Electrosurgical Laceration and Stabilization of MitraClip Followed by Valve Implantation for Iatrogenic Mitral Stenosis. JACC Cardiovasc Interv. 2021 Dec 7;S1936-8798(21)01895-1. https://doi.org/10.1016/j.jcin.2021.10.011

Rodríguez-Fernández JM, Danies E, Hoertel N, Galanter W, Saner H, Franco OH. Telemedicine Readiness Across Medical Conditions in a US National Representative Sample of Older Adults. J Appl Gerontol. 2021 Dec 2:7334648211056231. https://doi.org/10.1177/07334648211056231

Nydegger A, Novak U, Kronig MN, Legros M, Zeerleder S, Banz Y, Bacher U, Pabst T. Transformed Lymphoma Is Associated with a Favorable Response to CAR-T-Cell Treatment in DLBCL Patients. Cancers (Basel). 2021 Dec 2;13(23):6073. https://doi.org/10.3390/cancers13236073

Sundararaman SS, Peters LJF, Nazir S, Marquez AB, Bouma JE, Bayasgalan S, Döring Y, van der Vorst EPC. PCSK9 Imperceptibly Affects Chemokine Receptor Expression In Vitro and In Vivo. Int J Mol Sci. 2021 Dec 1;22(23):13026. https://doi.org/10.3390/ijms222313026

Bernhard B, Erdoes G, Radojewski P, Jung S, Schroth G, Gräni C. Extended Imaging Protocols to Elucidate Sources of Cardiovascular Embolism in the Work-up of Ischemic Stroke. Clin Neuroradiol. 2021 Dec;31(4):897-900. https://doi.org/10.1007/s00062-021-01103-4

Echeverría LE, Gómez-Ochoa SA, Rojas LZ, García-Rueda KA, López-Aldana P, Muka T, Morillo CA. Cardiovascular Biomarkers and Diastolic Dysfunction in Patients With Chronic Chagas Cardiomyopathy. Front Cardiovasc Med. 2021 Nov 29;8:751415. https://doi.org/10.3389/fcvm.2021.751415

Mohrez Y, Gloekler S, Schnupp S, Allakkis W, Liu XX, Fuerholz M, Brachmann J, Windecker S, Achenbach S, Meier B, Kleinecke C. Clinical benefit of left atrial appendage closure in octogenarians. J Geriatr Cardiol. 2021 Nov 28;18(11):886-896. doi: 10.11909/j.issn.1671-5411.2021.11.003.

Femiano R, Werner C, Wilhelm M, Eser P. Validation of open-source step-counting algorithms for wrist-worn tri-axial accelerometers in cardiovascular patients. Gait Posture. 2021 Nov 27;92:206-211. https://doi.org/10.1016/j.gaitpost.2021.11.035

Scutelnic A, Mattle HP, Branca M, Jung S, Reichlin T, Fischer U, Schankin CJ. Migraine and Atrial Fibrillation: a Systematic Review. Eur J Neurol. 2021 Nov 26; https://doi.org/10.1111/ene.15198

Rojas LZ, Gómez-Ochoa SA, Echeverría LE, Bautista-Niño PK, Hunziker L, Eisenga MF, Muka T. Circulating DHEA-S levels and major cardiovascular outcomes in chronic Chagas cardiomyopathy: A prospective cohort study. Int J Cardiol. 2021 Nov 25;S0167-5273(21)01870-2. https://doi.org/10.1016/j.ijcard.2021.11.054

Otsuka T, Bär S, Losdat S, Kavaliauskaite R, Ueki Y, Zanchin C, Lanz J, Praz F, Häner J, Siontis GCM, Zanchin T, Stortecky S, Pilgrim T, Windecker S, Räber L. Effect of Timing of Staged Percutaneous Coronary Intervention on Clinical Outcomes in Patients With Acute Coronary Syndromes. J Am Heart Assoc. 2021 Nov 24;e023129. https://doi.org/10.1161/jaha.121.023129

Mathys A, Bacher U, Banz Y, Legros M, Taleghani BM, Novak U, Pabst T. Outcome of patients with mantle cell lymphoma after autologous stem cell transplantation in the pre-CAR T-cell era Letter. Hematol Oncol. 2021 Nov 24. https://doi.org/10.1002/hon.2952

Valgimigli M, Cao D, Angiolillo DJ, Bangalore S, Bhatt DL, Ge J, Hermiller J, Makkar RR, Neumann F-J, Saito S, Picon H, Toelg R, Maksoud A, Chehab BM, Choi JW, Campo G, De la Torre Hernandez JM, Kunadian V, Sardella G, Thiele H, Varenne O, Vranckx P, Windecker S, Zhou Y, Krucoff MW, Ruster K, Zheng Y, Mehran R, XIENCE 90 and XIENCE 28 Investigators. Duration of Dual Antiplatelet Therapy for Patients at High Bleeding Risk Undergoing PCI. J Am Coll Cardiol. 2021 Nov 23;78(21):2060–72. https://doi.org/10.1016/j.jacc.2021.08.074

Iglesias JF, Degrauwe S, Cimci M, Chatelain Q, Roffi M, Windecker S, Pilgrim T. Differential Effects of Newer-Generation Ultrathin-Strut Versus Thicker-Strut Drug-Eluting Stents in Chronic and Acute Coronary Syndromes. JACC Cardiovasc Interv. 2021 Nov 22;14(22):2461–73. https://doi.org/10.1016/j.jcin.2021.09.028

Praz F, Muraru D, Kreidel F, Lurz P, Hahn RT, Delgado V, Senni M, von Bardeleben RS, Nickenig G, Hausleiter J, Mangieri A, Zamorano JL, Prendergast BD, Maisano F. Transcatheter treatment for tricuspid valve disease. EuroIntervention. 2021 Nov 19;17(10):791–808. https://doi.org/10.4244/eij-d-21-00695

Nanchen D, Carballo D, Bilz S, Rickli H, Koskinas KC, Mach F, Mueller C, Crljenica C, Rossi M, Reichert N, Sudano I. Effectiveness, Adherence, and Safety of Evolocumab in a Swiss Multicenter Prospective Observational Study. Adv Ther. 2021 Nov 18; https://doi.org/10.1007/s12325-021-01962-w

Harrell CR, Volarevic A, Djonov VG, Jovicic N, Volarevic V. Mesenchymal Stem Cell: A Friend or Foe in Anti-Tumor Immunity. Int J Mol Sci. 2021 Nov 18;22(22):12429. https://doi.org/10.3390/ijms222212429

Demirel C, Okuno T, Lanz J, Windecker S, Pilgrim T. Valve-in-Valve Transcatheter Aortic Valve Replacement for the Treatment of Paravalvular Leak Due to Ring Dehiscence. JACC Cardiovasc Interv. 2021 Nov 17;S1936-8798(21)01759-3. https://doi.org/10.1016/j.jcin.2021.09.015

Raut S, Katona É, Riches-Duit A, Coxon C, Muszbek L, Schroeder V, Rigsby P. An international collaborative study to assign value for Total Factor XIII-B Subunit Antigen to the WHO 1st International Standard for Factor XIII Plasma, (02/206): Communication from the ISTH SSC Subcommittee on Factor XIII and Fibrinogen. J Thromb Haemost. 2021 Nov 16; https://doi.org/10.1111/jth.15596

Asatryan B, Asimaki A, Landstrom AP, Khanji MY, Odening KE, Cooper LT, Marchlinski FE, Gelzer AR, Semsarian C, Reichlin T, Owens AT, Chahal CAA. Inflammation and Immune Response in Arrhythmogenic Cardiomyopathy: State-of-the-Art Review. Circulation. 2021 Nov 16;144(20):1646–55. https://doi.org/10.1161/circulationaha.121.055890

Räber L, Häner JD, Lüscher TF, Moccetti M, Roffi M, Stortecky S, Muller O, Garcia-Garcia HM, Waksman R, Siegrist P. A prospective, multicentre first-in-man study of the polymer-free ultrathin-strut BIOrapid stent (BIOVITESSE). EuroIntervention. 2021 Nov 15;EIJ-D-21-00537. EuroIntervention (pcronline.com)

Graf JR, Forster S, Bruehl FK, Banz Y, Hallal M, Brodard J, Bacher VU, Allam R, Schürch CM, Bonadies N. Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes. Cancers (Basel). 2021 Nov 15;13(22):5712. https://doi.org/10.3390/cancers13225712

I D, Okuno T, Heg D, Gräni C, Lanz J, Praz F, Stortecky S, Windecker S, Pilgrim T, Reineke D. Sinus of Valsalva Dimension and Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation: SOV dilatation in TAVI patients. Am Heart J. 2021 Nov 14;S0002-8703(21)00447-6. https://doi.org/10.1016/j.ahj.2021.11.004

Castaneda AB, Petty LE, Scholz M, Jansen R, Weiss S, Zhang X, Schramm K, Beutner F, Kirsten H, Schminke U, Hwang S-J, Marzi C, Dhana K, Seldenrijk A, Krohn K, Homuth G, Wolf P, Peters MJ, Dörr M, Peters A, van Meurs JBJ, Uitterlinden AG, Kavousi M, Levy D, Herder C, Grootheest G, Waldenberger M, Meisinger C, Rathmann W, Thiery J, Polak J, Koenig W, Seissler J, Bis JC, Franceshini N, Giambartolomei C, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Subclinical Working Group, Hofman A, Franco OH, Penninx BWJH, Prokisch H, Völzke H, Loeffler M, O’Donnell CJ, Below JE, Dehghan A, de Vries PS. Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues. Hum Mol Genet. 2021 Nov 12;ddab236. https://doi.org/10.1093/hmg/ddab236

Bano A, Rodondi N, Beer JH, Moschovitis G, Kobza R, Aeschbacher S, Baretella O, Muka T, Stettler C, Franco OH, Conte G, Sticherling C, Zuern CS, Conen D, Kühne M, Osswald S, Roten L, Reichlin T, of the Swiss‐Investigators. Association of Diabetes With Atrial Fibrillation Phenotype and Cardiac and Neurological Comorbidities: Insights From the Swiss-AF Study. J Am Heart Assoc. 2021 Nov 10;e021800. https://doi.org/10.1161/jaha.121.021800

Babic D, Hämmerli R, Santos Lopes B, Attenhofer Jost C, Tobler D, Schwerzmann M, Hasse B, Bonassin Tempesta F, Greutmann M. Impact of a structured patient education programme on early diagnosis of prosthetic pulmonary valve endocarditis. Cardiol Young. 2021 Nov 10;1–6. https://doi.org/10.1017/s1047951121004510

Vermathen M, von Tengg-Kobligk H, Hungerbühler MN, Vermathen P, Ruprecht N. 1H HR-MAS NMR Based Metabolic Profiling of Lung Cancer Cells with Induced and De-Induced Cisplatin Resistance to Reveal Metabolic Resistance Adaptations. Molecules. 2021 Nov 9;26(22):6766. https://doi.org/10.3390/molecules26226766

Seferović PM, Polovina M, Adlbrecht C, Bělohlávek J, Chioncel O, Goncalvesová E, Milinković I, Grupper A, Halmosi R, Kamzola G, Koskinas KC, Lopatin Y, Parkhomenko A, Põder P, Ristić AD, Šakalyt G, Trbušić M, Tundybayeva M, Vrtovec B, Yotov YT, Miličić D, Ponikowski P, Metra M, Rosano G, Coats AJ. Navigating between Scylla and Charybdis: challenges and strategies for implementing guideline-directed medical treatment in heart failure with reduced ejection fraction. Eur J Heart Fail. 2021 Nov 9; https://doi.org/10.1002/ejhf.2378

Laissue JA, Barré S, Bartzsch S, Blattmann H, Bouchet AM, Djonov VG, Haberthür D, Hlushchuk R, Kaser-Hotz B, Laissue PP, LeDuc G, Reding SO, Serduc R. Tolerance of Normal Rabbit Facial Bones and Teeth to Synchrotron X-Ray Microbeam Irradiation. Radiat Res. 2021 Nov 9; https://doi.org/10.1667/rade-21-00032.1

Bello C, Heinisch PP, Mihalj M, Carrel T, Luedi MM. Indoleamine-2,3-Dioxygenase as a Perioperative Marker of the Immune System. Front Physiol. 2021 Nov 8;12:766511. https://doi.org/10.3389/fphys.2021.766511

Colomé N, Abian J, Aloria K, Arizmendi JM, Barceló-Batllori S, Braga-Lagache S, Burlet-Schiltz O, Carrascal M, Casal JI, Chicano-Gálvez E, Chiva C, Clemente LF, Elortza F, Estanyol JM, Fernandez-Irigoyen J, Fernández-Puente P, Fidalgo MJ, Froment C, Fuentes M, Fuentes-Almagro C, Gay M, Hainard A, Heller M, Hernández ML, Ibarrola N, Iloro I, Kieselbach T, Lario A, Locard-Paulet M, Marina-Ramírez A, Martín L, Morato-López E, Muñoz J, Navajas R, Odena MA, Odriozola L, de Oliveira E, Paradela A, Pasquarello C, de Los Rios V, Ruiz-Romero C, Sabidó E, Sánchez Del Pino M, Sancho J, Santamaría E, Schaeffer-Reiss C, Schneider J, de la Torre C, Valero ML, Vilaseca M, Wu S, Wu L, Ximénez de Embún P, Canals F, Corrales FJ, ProteoRed-ISCIII, EuPA. Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis. J Proteomics. 2021 Nov 7;251:104409. https://doi.org/10.1016/j.jprot.2021.104409

Galea R, De Marco F, Meneveau N, Aminian A, Anselme F, Gräni C, Huber AT, Teiger E, Iriart X, Babongo Bosombo F, Heg D, Franzone A, Vranckx P, Fischer U, Pedrazzini G, Bedogni F, Räber L, Valgimigli M. Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: Primary Results of the SWISS-APERO Randomized Clinical Trial. Circulation. 2021 Nov 6; https://doi.org/10.1161/circulationaha.121.057859

Tokarska-Schlattner M, Kay L, Perret P, Isola R, Attia S, Lamarche F, Tellier C, Cottet-Rousselle C, Uneisi A, Hininger-Favier I, Foretz M, Dubouchaud H, Ghezzi C, Zuppinger C, Viollet B, Schlattner U. Role of Cardiac AMP-Activated Protein Kinase in a Non-pathological Setting: Evidence From Cardiomyocyte-Specific, Inducible AMP-Activated Protein Kinase α1α2-Knockout Mice. Front Cell Dev Biol. 2021 Nov 5;9:731015. https://doi.org/10.3389/fcell.2021.731015

Pahud de Mortanges A, Salvador D, Laimer M, Muka T, Wilhelm M, Bano A. The Role of SGLT2 Inhibitors in Atherosclerosis: A Narrative Mini-Review. Front Pharmacol. 2021 Nov 5;12:751214. https://doi.org/10.3389/fphar.2021.751214

He Y-Y, Xie X-M, Zhang H-D, Ye J, Gencer S, van der Vorst EPC, Döring Y, Weber C, Pang X-B, Jing Z-C, Yan Y, Han Z-Y. Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Front Pharmacol. 2021 Nov 5;12:753727. https://doi.org/10.3389/fphar.2021.753727

Shrestha NR, Uranw S, Karki P, Bastola S, Mahato R, Sherpa K, Dhungana S, Gurung K, Pandey N, Agrawal K, Bartkowiak J, Shah P, Rothenbühler M, Pilgrim T. Prevalence of latent structural heart disease in Nepali schoolchildren. Cardiol Young. 2021 Nov 4;1–3. https://doi.org/10.1017/s1047951121004479

De Marinis D, Obrist D. Data Assimilation by Stochastic Ensemble Kalman Filtering to Enhance Turbulent Cardiovascular Flow Data From Under-Resolved Observations. Front Cardiovasc Med. 2021 Nov 2;8:742110. https://doi.org/10.3389/fcvm.2021.742110

Gu SZ, Costopoulos C, Huang Y, Bourantas C, Woolf A, Sun C, Teng Z, Losdat S, Räber L, Samady H, Bennett MR. High-intensity statin treatment is associated with reduced plaque structural stress and remodelling of artery geometry and plaque architecture. European Heart Journal Open, 2021 Nov; 1(3), oeab039, https://doi.org/10.1093/ehjopen/oeab039

Belch JJF, Brodmann M, Baumgartner I, Binder CJ, Casula M, Heiss C, Kahan T, Parini P, Poredos P, Catapano AL, Tokgözoğlu L. Lipid-lowering and anti-thrombotic therapy in patients with peripheral arterial disease. Vasa. 2021 Nov 1;50(6):401–11. https://doi.org/10.1024/0301-1526/a000969

Zheng S, Carugo D, Mosayyebi A, Turney B, Burkhard F, Lange D, Obrist D, Waters S, Clavica F. Fluid mechanical modeling of the upper urinary tract. WIREs Mech Dis. 2021 Nov;13(6):e1523. https://doi.org/10.1002/wsbm.1523

Wright MD, Romanelli P, Bravin A, Le Duc G, Brauer-Krisch E, Requardt H, Bartzsch S, Hlushchuk R, Laissue J-A, Djonov V. Non-conventional Ultra-High Dose Rate (FLASH) Microbeam Radiotherapy Provides Superior Normal Tissue Sparing in Rat Lung Compared to Non-conventional Ultra-High Dose Rate (FLASH) Radiotherapy. Cureus. 2021 Nov;13(11):e19317. https://doi.org/10.7759/cureus.19317

Rodriguez-Morales AJ, Franco OH. Public trust, misinformation and COVID-19 vaccination willingness in Latin America and the Caribbean: today’s key challenges. Lancet Reg Health Am. 2021 Nov 3;3:100073. https://doi.org/10.1016/j.lana.2021.100073

Rössler J, Baumgartner I, Kremer Hovinga JA. EHA Endorsement of the Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. Hemasphere. 2021 Nov 1;5(11):e647. https://doi.org/10.1097/hs9.0000000000000647

Mihalj M, Mosbahi S, Schmidli J, Heinisch PP, Reineke D, Schoenhoff F, Kadner A, Schefold JC, Räber L, Potapov EV, Luedi MM. Providing safe perioperative care in cardiac surgery during the COVID-19 pandemic. Best Pract Res Clin Anaesthesiol. 2021 Oct 30;35(3):321–32. https://doi.org/10.1016/j.bpa.2021.01.002

Niederseer D, Walser R, Schmied C, Dela F, Gräni C, Bohm P, Müller E, Niebauer J. Effects of a 12-Week Recreational Skiing Program on Cardio-Pulmonary Fitness in the Elderly: Results from the Salzburg Skiing in the Elderly Study (SASES). Int J Environ Res Public Health. 2021 Oct 29;18(21):11378. https://doi.org/10.3390/ijerph182111378

Atef H, Muka T. Reduced-Exertion High-Intensity Interval Training as a Novel Therapeutic Approach for Insomnia. Front Psychiatry. 2021 Oct 29;12:754171. https://doi.org/10.3389/fpsyt.2021.754171

Wolf TG, Anderegg AL, Haberthür D, Khoma OZ, Schumann S, Boemke N, Wierichs RJ, Hlushchuk R. Internal morphology of 101 mandibular canines of a Swiss-German population by means of micro-CT: An ex vivo study. Sci Rep. 2021 Oct 28;11(1):21281. https://doi.org/10.1038/s41598-021-00758-w

Asami M, Bernhard B, Demirel C, Okuno T, Stortecky S, Heg D, Tomii D, Reineke D, Praz F, Lanz J, Windecker S, Gräni C, Pilgrim T. Clinical outcomes following transcatheter aortic valve implantation in patients with porcelain aorta. J Cardiovasc Comput Tomogr. 2021 Oct 28;S1934-5925(21)00451-2. https://doi.org/10.1016/j.jcct.2021.10.006

Echeverría LE, Rojas LZ, Gómez-Ochoa SA, Rueda-Ochoa OL, Sosa-Vesga CD, Muka T, Januzzi JL, Marcus R, Morillo CA. Cardiovascular biomarkers as predictors of adverse outcomes in chronic Chagas cardiomyopathy. PLoS One. 2021 Oct 28;16(10):e0258622. https://doi.org/10.1371/journal.pone.0258622

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Heinisch PP, Mihalj M, Huber M, Schefold JC, Hartmann A, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Impact of Lipoprotein(a) Levels on Perioperative Outcomes in Cardiac Surgery. Cells. 2021 Oct 21;10(11):2829. https://doi.org/10.3390/cells10112829

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Hill V, Akarsu H, Barbarroja RS, Cippà VL, Kuhnert P, Heller M, Falquet L, Heller M, Stoffel MH, Labroussaa F, Jores J. Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems. PLoS Genet. 2021 Oct 21;17(10):e1009365. https://doi.org/10.1371/journal.pgen.1009365

Pilgrim T, Okuno T. Transcatheter paravalvular leak closure: catch me if you can. EuroIntervention. 2021 Oct 20;17(9):699–700. https://doi.org/10.4244/eijv17i9a121

Messmer AS, Que Y-A, Schankin C, Banz Y, Bacher U, Novak U, Pabst T. Novel Adaptive T-Cell Oncological Treatments Lead to New Challenges for Medical Emergency Teams: A 2-Year Experience From a Tertiary-Care Hospital in Switzerland. Crit Care Explor. 2021 Oct 20;3(10):e0552. https://doi.org/10.1007/s00508-021-01948-2

Sticchi A, Bartkowiak J, Brugger N, Weiss S, Windecker S, Praz F. Retrograde Retrieval of a Novel Large Mitral Clip After Embolization Into the Left Ventricle. JACC Case Rep. 2021 Oct 20;3(14):1561-1568. https://doi.org/10.1016/j.jaccas.2021.08.024

Romano M, Bravin DA, Wright DMD, Jacques L, Miettinen DA, Hlushchuk DR, Dinkel J, Bartzsch DS, Laissue JA, Djonov V, Coan DP. X-ray Phase Contrast 3D virtual histology: evaluation of lung alterations after micro-beam irradiation. Int J Radiat Oncol Biol Phys. 2021 Oct 19;S0360-3016(21)02914-X. https://doi.org/10.1016/j.ijrobp.2021.10.009

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Schniering J, Maciukiewicz M, Gabrys HS, Brunner M, Blüthgen C, Meier C, Braga-Lagache S, Uldry A-C, Heller M, Guckenberger M, Fretheim H, Nakas CT, Hoffmann-Vold A-M, Distler O, Frauenfelder T, Tanadini-Lang S, Maurer B. Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis. Eur Respir J. 2021 Oct 14;2004503. https://doi.org/10.1183/13993003.04503-2020

Fischer K, Neuenschwander MD, Jung C, Hurni S, Winkler BM, Huettenmoser SP, Jung B, Vogt AP, Eberle B, Guensch DP. Assessment of Myocardial Function During Blood Pressure Manipulations Using Feature Tracking Cardiovascular Magnetic Resonance. Front Cardiovasc Med. 2021 Oct 12;8:743849. https://doi.org/10.3389/fcvm.2021.743849

Pithon A, McCann A, Buttu A, Vesin JM, Pascale P, Le Bloa M, Herrera C, Park CI, Roten L, Kühne M, Spies F, Knecht S, Sticherling C, Pruvot E, Luca A. Dynamics of Intraprocedural Dominant Frequency Identifies Ablation Outcome in Persistent Atrial Fibrillation. Front Physiol. 2021 Oct 12;12:731917. https://doi.org/10.3389/fphys.2021.731917

Asatryan B, Odening KE, Reichlin T. Myocardial Histopathology Studies in Brugada Syndrome Decedents: Structural Features of a Presumed Electrical Disease. J Am Coll Cardiol. 2021 Oct 12;78(15):1522–4. https://doi.org/10.1016/j.jacc.2021.08.016

Bundo M, de Schrijver E, Federspiel A, Toreti A, Xoplaki E, Luterbacher J, Franco OH, Müller T, Vicedo-Cabrera AM. Ambient temperature and mental health hospitalizations in Bern, Switzerland: A 45-year time-series study. PLoS One. 2021 Oct 12;16(10):e0258302. https://doi.org/10.1371/journal.pone.0258302

Mihalj M, Heinisch PP, Huber M, Schefold JC, Hartmann A, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Effect of Perioperative Lipid Status on Clinical Outcomes after Cardiac Surgery. Cells. 2021 Oct 11;10(10):2717. https://doi.org/10.3390/cells10102717

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Piccolo R, Bonaa KH, Efthimiou O, Varenne O, Urban P, Kaiser C, Räber L, de Belder A, Remkes W, Van’t Hof AWJ, Stankovic G, Lemos PA, Wilsgaard T, Reifart J, Rodriguez AE, Ribeiro EE, Serruys PWJC, Abizaid A, Sabaté M, Byrne RA, de la Torre Hernandez JM, Wijns W, Esposito G, Jüni P, Windecker S, Valgimigli M; Drug-Eluting or Bare-Metal Stents for Left Anterior Descending or Left Main Coronary Artery Revascularization. J Am Heart Assoc. 2021 Oct 8;e018828. https://doi.org/10.1161/jaha.120.018828

Nucera M, Meuli L, Janka H, Schindewolf M, Schmidli J, Makaloski V. Comprehensive review with pooled analysis on external and internal jugular vein aneurysm. J Vasc Surg Venous Lymphat Disord. 2021 Oct 8;S2213-333X(21)00502-3. https://doi.org/10.1016/j.jvsv.2021.09.009

Lüscher TF, Davies A, Beer JH, Valgimigli M, Nienaber CA, Camm JA, Baumgartner I, Diener H-C, Konstantinides SV. Towards personalized antithrombotic management with drugs and devices across the cardiovascular spectrum. Eur Heart J. 2021 Oct 8;ehab642. https://doi.org/10.1093/eurheartj/ehab642

Klingenberg R, Aghlmandi S, Räber L, Akhmedov A, Gencer B, Carballo D, Nanchen D, Bucher HC, Rodondi N, Mach F, Windecker S, Landmesser U, von Eckardstein A, Hamm CW, Lüscher TF, Matter CM. Cysteine-Rich Angiogenic Inducer 61 Improves Prognostic Accuracy of GRACE (Global Registry of Acute Coronary Events) 2.0 Risk Score in Patients With Acute Coronary Syndromes. J Am Heart Assoc. 2021 Oct 8;e020488. https://doi.org/10.1161/jaha.120.020488

Worni-Schudel I, Tzalis V, Jakob J, Tal K, Gilgien-Dénéréaz L, Gencer B, Matter CM, Lüscher TF, Windecker S, Mach F, Humair JP, Rodondi N, Nanchen D, Auer R. Association between self-reported motivation to quit smoking with effectiveness of smoking cessation intervention among patients hospitalized for acute coronary syndromes in Switzerland. Prev Med Rep. 2021 Oct 7;24:101583. https://doi.org/10.1016/j.pmedr.2021.101583

Won-Keun Kim, Thomas Walther, Christof Burgdorf, Helge Möllmann, Axel Linke, Simon Redwood, Christian Thilo, Michael Hilker, Michael Joner, Holger Thiele, Lars Conzelmann, Lenard Conradi, Sebastian Barth, Bernard Prendergast, Oliver Husser, Stefan Stortecky, Tobias Rheude, Johannes Blumenstein, Dik Heg, Stephan Windecker, Thomas Pilgrim, Jonas Lanz, SCOPE I Investigators. Predictors of Prosthetic Valve Regurgitation After Transcatheter Aortic Valve Implantation With ACURATE neo in the SCOPE I Trial. JACC Cardiovasc Imaging. 2021 Oct 7;S1936-878X(21)00686-0. https://doi.org/10.1016/j.jcmg.2021.08.019

Greulich S, Gatidis S, Gräni C, Blankstein R, Glatthaar A, Mezger K, Müller KAL, Castor T, Mahrholdt H, Häntschel M, Hetzel J, Dittmann H, Nikolaou K, Gawaz M, la Fougère C, Krumm P. Hybrid Cardiac Magnetic Resonance/Fluorodeoxyglucose Positron Emission Tomography to Differentiate Active From Chronic Cardiac Sarcoidosis. JACC Cardiovasc Imaging. 2021 Oct 7;S1936-878X(21)00685-9. https://doi.org/10.1016/j.jcmg.2021.08.018

Blanco PJ, Ziemer PGP, Bulant CA, Ueki Y, Bass R, Räber L, Lemos PA, García-García HM. Fully automated lumen and vessel contour segmentation in intravascular ultrasound datasets. Med Image Anal. 2021 Oct 7;75:102262. https://doi.org/10.1016/j.media.2021.102262

Anghel N, Müller J, Serricchio M, Jelk J, Bütikofer P, Boubaker G, Imhof D, Ramseier J, Desiatkina O, Păunescu E, Braga-Lagache S, Heller M, Furrer J, Hemphill A. Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. Int J Mol Sci. 2021 Oct 5;22(19):10787. https://doi.org/10.3390/ijms221910787

Abbas AE, Mando R, Kadri A, Khalili H, Hanzel G, Shannon F, Al-Azizi K, Waggoner T, Kassas S, Pilgrim T, Okuno T, Camacho A, Selberg A, Elmariah S, Bavry A, Ternacle J, Christensen J, Gheewala N, Pibarot P, Mack M. Comparison of Transvalvular Aortic Mean Gradients Obtained by Intraprocedural Echocardiography and Invasive Measurement in Balloon and Self-Expanding Transcatheter Valves. J Am Heart Assoc. 2021 Oct 5;10(19):e021014. https://doi.org/10.1161/JAHA.120.021014

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Castiglione A, Hornyik T, Wülfers EM, Giammarino L, Edler I, Jowais JJ, Rieder M, Perez-Feliz S, Koren G, Bősze Z, Varró A, Zehender M, Brunner M, Bode C, Liin SI, Larsson HP, Baczkó I, Odening KE. Docosahexaenoic acid normalizes QT interval in long QT type 2 transgenic rabbit models in a genotype-specific fashion. Europace. 2021 Oct 3;euab228. https://doi.org/10.1093/europace/euab228

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Wild MG, Gloeckler M, Wustmann KB, Erne SA, Grogg H, Huber AT, Windecker S, Praz F, Gräni C. Multimodality Imaging for Evaluation of Bicaval Valved Stent Implantation in Severer Tricuspid Regurgitation. J Am Coll Cardiol Case Rep. 2021 Oct, 3 (13) 1512-1518. https://doi.org/10.1016/j.jaccas.2021.07.009

Mahendiran T, Klingenberg R, Nanchen D, Gencer B, Meier D, Räber L, Carballo D, Matter CM, Lüscher TF, Mach F, Rodondi N, Muller O, Fournier S. CCN family member 1 (CCN1) is an early marker of infarct size and left ventricular dysfunction in STEMI patients. Atherosclerosis. 2021 Oct;335:77-83. https://doi.org/10.1016/j.atherosclerosis.2021.09.019

Senk A, Djonov V. Collagen fibers provide guidance cues for capillary regrowth during regenerative angiogenesis in zebrafish. Sci Rep. 2021 Sep 30;11(1):19520. https://doi.org/10.1038/s41598-021-98852-6

Conedera FM, Pousa AMQ, Mercader N, Tschopp M, Enzmann V. The TGFbeta/Notch axis facilitates Muller cell-to-epithelial transition to ultimately form a chronic glial scar. Mol Neurodegener. 2021 Sep 30;16(1):69. https://doi.org/10.1186/s13024-021-00482-z

Draxler DF, Stortecky S. Interventional Reperfusion Strategies for Acute Pulmonary Embolism. Praxis (Bern 1994). 2021 Sep 29;110(13):743-751. https://doi.org/10.1024/1661-8157/a003737

Krisai P, Roten L, Zeljkovic I, Pavlovic N, Ammann P, Reichlin T, Auf der Maur E, Streicher O, Knecht S, Kühne M, Osswald S, Novak J, Sticherling C. Prospective Evaluation of a Standardized Screening for Atrial Fibrillation after Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter. J Clin Med. 2021 Sep 28;10(19):4453. https://doi.org/10.3390/jcm10194453

Govsyeyev N, Nehler MR, Low Wang CC, Kavanagh S, Hiatt WR, Long C, Jones WS, Fowkes FGR, Berger JS, Baumgartner I, Patel MR, Goodney PP, Beckman JA, Katona BG, Mahaffey KW, Blomster J, Norgren L, Bonaca MP. Etiology and Outcomes of Amputation in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial. J Vasc Surg. 2021 Sep 28:S0741-5214(21)02161-3. https://doi.org/10.1016/j.jvs.2021.08.096

Lanz J, Reardon MJ, Pilgrim T, Stortecky S, Deeb GM, Chetcuti S, Yakubov SJ, Gleason TG, Huang J, Windecker S. Incidence and Outcomes of Infective Endocarditis After Transcatheter or Surgical Aortic Valve Replacement. J Am Heart Assoc. 2021 Sep 28;e020368. https://doi.org/10.1161/jaha.120.020368

Sticchi A, Praz F, Reineke D, Windecker S. Learning From Failure at the CUTTING-EDGE of Transcatheter Mitral Valve Therapies. JACC Cardiovasc Interv. 2021 Sep 27;14(18):2022–6. https://doi.org/10.1016/j.jcin.2021.08.033

Aguirre Sánchez L, Roa-Díaz ZM, Gamba M, Grisotto G, Moreno Londoño AM, Mantilla-Uribe BP, Rincón Méndez AY, Ballesteros M, Kopp-Heim D, Minder B, Suggs LS, Franco OH. What Influences the Sustainable Food Consumption Behaviours of University Students? A Systematic Review. Int J Public Health. 2021 Sep 23;66:1604149. https://doi.org/10.3389/ijph.2021.1604149

Roa-Díaz ZM, Asllanaj E, Amin HA, Rojas LZ, Nano J, Ikram MA, Drenos F, Franco OH, Pazoki R, Marques-Vidal P, Voortman T, Muka T. Age at Natural Menopause and Blood Pressure Traits: Mendelian Randomization Study. J Clin Med. 2021 Sep 22;10(19):4299. https://doi.org/10.3390/jcm10194299

Vranckx P, Valgimigli M, Odutayo A, Serruys PW, Hamm C, Steg PG, Heg D, Mc Fadden EP, Onuma Y, Benit E, Janssens L, Diletti R, Ferrario M, Huber K, Räber L, Windecker S, Jüni P, GLOBAL LEADERS Investigators. Efficacy and Safety of Ticagrelor Monotherapy by Clinical Presentation: Pre-Specified Analysis of the GLOBAL LEADERS Trial. J Am Heart Assoc. 2021 Sep 21;10(18):e015560. https://doi.org/10.1161/jaha.119.015560

Okuno T, Overtchouk P, Asami M, Tomii D, Stortecky S, Praz F, Lanz J, Siontis GCM, Gräni C, Windecker S, Pilgrim T. Deep learning-based prediction of early cerebrovascular events after transcatheter aortic valve replacement. Sci Rep. 2021 Sep 21;11(1):18754. https://doi.org/10.1038/s41598-021-98265-5

Catucci D, Obmann VC, Berzigotti A, Gräni C, Guensch DP, Fischer K, Ebner L, Heverhagen JT, Christe A, Huber AT. Noninvasive assessment of clinically significant portal hypertension using ΔT1 of the liver and spleen and ECV of the spleen on routine Gd-EOB-DTPA liver MRI. Eur J Radiol. 2021 Sep 20;144:109958.  https://doi.org/10.1016/j.ejrad.2021.109958

Ivanovic E, Kucera JP. Localization of Na+ channel clusters in narrowed perinexi of gap junctions enhances cardiac impulse transmission via ephaptic coupling: a model study. J Physiol. 2021 Sep 17; https://doi.org/10.1113/jp282105

Vynckier J, Kaesmacher J, Wardlaw JM, Roten L, Beyeler M, Belachew NF, Grunder L, Seiffge DJ, Jung S, Gralla J, Dobrocky T, Heldner MR, Prange U, Goeldlin MB, Arnold M, Fischer U, Meinel TR. Phenotypes of Chronic Covert Brain Infarction in Patients With First-Ever Ischemic Stroke: A Cohort Study. Stroke. 2021 Sep 16;STROKEAHA121034347. https://doi.org/10.1161/strokeaha.121.034347

Vahanian A, Praz F, Milojevic M, Beyersdorf F. The “ten commandments” for the 2021 ESC/EACTS Guidelines on valvular heart disease. Eur Heart J. 2021 Sep 16;ehab626. https://doi.org/10.1093/eurheartj/ehab626

Freund A, Pöss J, de Waha-Thiele S, Meyer-Saraei R, Fuernau G, Eitel I, Feistritzer H-J, Rubini M, Huber K, Windecker S, Montalescot G, Oldroyd K, Noc M, Zeymer U, Ouarrak T, Schneider S, Baran DA, Desch S, Thiele H. Comparison of risk prediction models in infarct-related cardiogenic shock. Eur Heart J Acute Cardiovasc Care. 2021 Sep 16;zuab054. https://doi.org/10.1093/ehjacc/zuab054

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Charlesworth M, Hayes T, Erdoes G. Reversal Agents for the Management of Direct Oral Anticoagulant-Related Bleeding in Cardiac Surgical Patients: The Emperor's New Clothes? J Cardiothorac Vasc Anesth. 2021 Apr 11:S1053-0770(21)00332-3. https://doi.org/10.1053/j.jvca.2021.04.007

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Asatryan B, Rieder M, Castiglione A, Odening KE. Arrhythmic risk during pregnancy and postpartum in patients with long QT syndrome. Herzschrittmacherther Elektrophysiol. 2021 Mar 29. https://doi.org/10.1007/s00399-021-00757-4

Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, Abriel H. Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes. Int J Mol Sci. 2021 Mar 26;22(7):3401. https://doi.org/10.3390/ijms22073401

Tönz GM, Kadner A, Pfammatter J-P, Agyeman PKA. Invasive Bacterial and Fungal Infections After Pediatric Cardiac Surgery: A Single-center Experience. Pediatr Infect Dis J. 2021 Apr 1;40(4):310–6. https://doi.org/10.1097/INF.0000000000003005

Gargiulo G, Nagler M, Valgimigli M. Response by Gargiulo et al to Letter Regarding Article, “Cangrelor, Tirofiban, and Chewed or Standard Prasugrel Regimens in Patients With ST-Segment-Elevation Myocardial Infarction: Primary Results of the FABOLUS FASTER Trial.” Circulation. 2021 Mar 30;143(13):e797–8. https://doi.org/10.1161/CIRCULATIONAHA.120.051945

Corpataux N, Brugger N, Hunziker L, Reineke D, Windecker S, Vahanian A, Praz F. The role of transcatheter mitral valve leaflet approximation for the treatment of secondary mitral regurgitation: current status and future prospects. Expert Rev Med Devices. 2021 Mar 26;1– https://doi.org/10.1080/17434440.2021.1899804

Koskinas KC, Gencer B, Nanchen D, Branca M, Carballo D, Klingenberg R, Blum MR, Carballo S, Muller O, Matter CM, Lüscher TF, Rodondi N, Heg D, Wilhelm M, Räber L, Mach F, Windecker S. Eligibility for PCSK9 inhibitors based on the 2019 ESC/EAS and 2018 ACC/AHA guidelines. Eur J Prev Cardiol. 2021 Mar 23;28(1):59–65. https://doi.org/10.1177/2047487320940102  

Kim W-K, Walther T, Burgdorf C, Möllmann H, Linke A, Redwood S, Thilo C, Hilker M, Joner M, Thiele H, Conzelmann L, Conradi L, Kerber S, Schymik G, Prendergast B, Husser O, Blumenstein J, Stortecky S, Heg D, Künzi A, Jüni P, Windecker S, Pilgrim T, Lanz J, SCOPE I Investigators. One-Year Outcomes of a Randomized Trial Comparing a Self-Expanding With a Balloon-Expandable Transcatheter Aortic Valve. Circulation. 2021 Mar 23;143(12):1267–9. https://doi.org/10.1161/CIRCULATIONAHA.120.052251

Bär S, Praz F, Räber L. Plaque erosion causing ST-elevation myocardial infarction after consumption of cannabis and N2O in a 27-year old man: a case report. BMC Cardiovasc Disord. 2021 Mar 23;21(1):147. https://doi.org/10.1186/s12872-021-01953-3  

Otsuka T, Ueki Y, Kavaliauskaite R, Zanchin T, Bär S, Stortecky S, Pilgrim T, Valgimigli M, Meier B, Heg D, Windecker S, Räber L. Single antiplatelet therapy with use of prasugrel in patients undergoing percutaneous coronary intervention. Catheter Cardiovasc Interv. 2021 Mar 22; https://doi.org/10.1002/ccd.29650

Vincentz JW, Firulli BA, Toolan KP, Osterwalder M, Pennacchio LA, Firulli AB. HAND transcription factors cooperatively specify the aorta and pulmonary trunk. Dev Biol. 2021 Mar 20; https://doi.org/10.1016/j.ydbio.2021.03.011

Del Val D, Abdel-Wahab M, Linke A, Durand E, Ihlemann N, Urena M, Pellegrini C, Giannini F, Landt M, Auffret V, Sinning JM, Cheema A, Nombela-Franco L, Chamandi C, Campelo-Parada F, Munoz-Garcia A, et al. Temporal Trends, Characteristics, and Outcomes of Infective Endocarditis After Transcatheter Aortic Valve Replacement. Clin Infect Dis. 2021 Mar 18; https://doi.org/10.1093/cid/ciaa1941  

Coats AJS, Anker SD, Baumbach A, Alfieri O, von Bardeleben RS, Bauersachs J, Bax JJ, Boveda S, Čelutkienė J, Cleland JG, Dagres N, Deneke T, Farmakis D, Filippatos G, Hausleiter J, Hindricks G, et al. The management of secondary mitral regurgitation in patients with heart failure: a joint position statement from the Heart Failure Association (HFA), European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA), and Eur. Eur Heart J. 2021 Mar 18; https://doi.org/10.1093/eurheartj/ehab086

Vullo S, Ambrosio N, Kucera JP, Bignucolo O, Kellenberger S. Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate. Elife. 2021 Mar 17;10. https://doi.org/10.7554/eLife.66488

Galea R, Gräni C. Device neo-endothelialization after left atrial appendage closure: the role of cardiac computed tomography angiography. Int J Cardiovasc Imaging. 2021 Mar 17; https://doi.org/10.1007/s10554-021-02206-2

Kou J, Wang M, Shi J, Zhang H, Pu X, Song S, Yang C, Yan Y, Döring Y, Xie X, Pang X. Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega. 2021 Mar 16;6(10):6654–62. https://doi.org/10.1021/acsomega.0c04810

Kuno T, Claessen B, Cao D, Chandiramani R, Guedeney P, Sorrentino S, Krucoff M, Kozuma K, Ge J, Seth A, Makkar R, Bangalore S, Bhatt DL, Angiolillo DJ, Saito S, Neumann F-J, Hermiller J, Rau V, Ruster K, Wang J, Valgimigli M, Mehran R. Impact of renal function in high bleeding risk patients undergoing percutaneous coronary intervention: a patient-level stratified analysis from four post-approval studies. J Thromb Thrombolysis. 2021 Mar 11; https://doi.org/10.1007/s11239-020-02321-2

Tholl MV, Zurbuchen A, Tanner H, Haeberlin A. Potential of subdermal solar energy harvesting for medical device applications based on worldwide meteorological data. J Biomed Opt. 2021 Mar 10;26(3). https://doi.org/10.1117/1.JBO.26.3.038002

Grisotto G, Raguindin PF, Glisic M, Bally L, Bano A, Franco OH, Marques-Vidal P, Muka T. Menopausal Transition Is Not Associated with Dietary Change in Swiss Women. J Nutr. 2021 Mar 9; https://doi.org/10.1093/jn/nxab003

Schwerzmann M, Ruperti-Repilado FJ, Baumgartner H, Bouma B, Bouchardy J, Budts W, Campens L, Chessa M, Del Cerro Marin MJ, Gabriel H, Gallego P, Garcia-Orta R, Gonzalez AE, Jensen AS, Ladouceur M, Miranda-Barrio B, Morissens M, Pasquet A, Rueda J, van den Bosch AE, van der Zwaan HB, Tobler D, Greutmann M, EPOCH. Clinical outcome of COVID-19 in patients with adult congenital heart disease. Heart. 2021 Mar 8; https://doi.org/10.1136/heartjnl-2020-318467

Benz E, Trajanoska K, Schoufour JD, Lahousse L, de Roos EW, Terzikhan N, Medina-Gomez C, Verhamme K, Williams R, Stricker BH, Franco OH, Ikram MA, Rivadeneira F, Brusselle G. Sarcopenia in older people with chronic airway diseases: the Rotterdam study. ERJ Open Res. 2021 Mar 8;7(1):00522-2020. eCollection 2021 Jan. https://doi.org/10.1183/23120541.00522-2020

Kohler P, Wolfensberger A, Stampf S, Brönnimann A, Boggian K, van Delden C, Favre M, Hirzel C, Khanna N, Kuster SP, Manuel O, Neofytos D, Ragozzino S, Schreiber PW, Walti L, Mueller NJ, Swiss Transplant Cohort Study. Temporal trends, risk factors and outcomes of infections due to extended-spectrum β-lactamase producing Enterobacterales in Swiss solid organ transplant recipients between 2012 and 2018. Antimicrob Resist Infect Control. 2021 Mar 7;10(1):50. https://doi.org/10.1186/s13756-021-00918-7   

Asatryan B, Seiler J, Bourquin L, Knecht S, Servatius H, Madaffari A, Baldinger SH, Badertscher P, Küffer T, Spies F, Tanner H, Kühne M, Osswald S, Roten L, Sticherling C, Reichlin T. Pre-procedural arrhythmia burden and the outcome of catheter ablation of idiopathic premature ventricular complexes. Pacing Clin Electrophysiol. 2021 Mar 6; https://doi.org/10.1111/pace.14211

Pilgrim T, Muller O, Heg D, Roffi M, Kurz DJ, Moarof I, Weilenmann D, Kaiser C, Tapponnier M, Losdat S, Eeckhout E, Valgimigli M, Jüni P, Windecker S, Iglesias JF. Biodegradable- Versus Durable-Polymer Drug-Eluting Stents for STEMI: Final 2-Year Outcomes of the BIOSTEMI Trial. JACC Cardiovasc Interv. 2021 Mar 5; https://doi.org/10.1016/j.jcin.2020.12.011  

Leonardi S, Capodanno D, Sousa-Uva M, Vrints C, Rex S, Guarracino F, Bueno H, Lettino M, Price S, Valgimigli M, Jeppsson A. Composition, structure, and function of heart teams: a joint position paper of the ACVC, EAPCI, EACTS, and EACTA focused on the management of patients with complex coronary artery disease requiring myocardial revascularization. Eur Heart J Acute Cardiovasc Care. 2021 Mar 5;10(1):83–93. https://doi.org/10.1093/ehjacc/zuaa013  

Karam N, Orban M, Kalbacher D, Butter C, Praz F, Lubos E, Bannehr M, Kassar M, Petrescu A, Iliadis C, Unterhuber M, Asselin A, Thiele H, Pfister R, Windecker S, Lurz P, von Bardeleben S, Hausleiter J, EuroSMR investigators. Impact of effective regurgitant orifice area on outcome of secondary mitral regurgitation transcatheter repair. Clin Res Cardiol. 2021 Mar 4; https://doi.org/10.1007/s00392-021-01807-0

Brune MM, Stüssi G, Lundberg P, Vela V, Heim D, Manz MG, Haralambieva E, Pabst T, Banz Y, Bargetzi M, Grobholz R, Fehr M, Cogliatti S, Ossenkoppele GJ, Löwenberg B, Rudolf CB, Li Q, Passweg J, Mazzuchelli L, Medinger M, Tzankov A, Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK). Effects of lenalidomide on the bone marrow microenvironment in acute myeloid leukemia: Translational analysis of the HOVON103 AML/SAKK30/10 Swiss trial cohort. Ann Hematol. 2021 Mar 2; https://doi.org/10.1007/s00277-021-04467-2  

Patel PA, Henderson RA Jr, Bolliger D, Erdoes G, Mazzeffi MA. The Year in Coagulation: Selected Highlights from 2020. J Cardiothorac Vasc Anesth. 2021 Mar 2:S1053-0770(21)00192-0. https://doi.org/10.1053/j.jvca.2021.02.057

Kohler C, Wyss TR, Mertineit N, Makaloski V, Schmidli J. Emergent open conversion for stent-graft deployment failure in a ruptured thoracic aneurysm. J Vasc Surg Cases Innov Tech. 2021 Mar 1;7(1):180–2. https://doi.org/10.1016/j.jvscit.2020.10.017

Kirtane AJ, Stoler R, Feldman R, Neumann F-J, Boutis L, Tahirkheli N, Toelg R, Othman I, Stein B, Choi JW, Windecker S, Yeh RW, Dauerman HL, Price MJ, Underwood P, Allocco D, Meredith I, Kereiakes DJ. Primary Results of the EVOLVE Short DAPT Study: Evaluation of 3-Month Dual Antiplatelet Therapy in High Bleeding Risk Patients Treated With a Bioabsorbable Polymer-Coated Everolimus-Eluting Stent. Circ Cardiovasc Interv. 2021 Mar 1;14(3):e010144. https://doi.org/10.1161/CIRCINTERVENTIONS.120.010144

Bigler MR, Huber AT, Räber L, Gräni C. A case report of a symptomatic right anomalous coronary artery with concomitant atherosclerotic disease: the benefit of a sequential comprehensive non-invasive and invasive diagnostic approach. Eur Heart J Case Rep. 2021 Mar 1;5(3):ytab081. https://doi.org/10.1093/ehjcr/ytab081

Harrell CR, Djonov V, Volarevic V. The Cross-Talk between Mesenchymal Stem Cells and Immune Cells in Tissue Repair and Regeneration. Int J Mol Sci. 2021 Mar 1;22(5):2472. https://doi.org/10.3390/ijms22052472

Erdoes G, Birschmann I, Nagler M, Koster A. Andexanet Alfa-Induced Heparin Resistance: When Anticoagulation Really Remains Reversed. J Cardiothorac Vasc Anesth. 2021 Mar;35(3):908-909. Epub 2020 Nov 28. https://doi.org/10.1053/j.jvca.2020.11.052

Gebhart I, Götting C, Hool S-L, Morrison M, Korda A, Caversaccio M, Obrist D, Mantokoudis G. Sémont Maneuver for Benign Paroxysmal Positional Vertigo Treatment: Moving in the Correct Plane Matters. Otol Neurotol. 2021 Mar 1;42(3):e341–7. https://doi.org/10.1097/mao.0000000000002992

Pedretti RFE, Iliou M-C, Israel CW, Abreu A, Miljoen H, Corrà U, Stellbrink C, Gevaert AB, Theuns DA, Piepoli MF, Reibis R, Schmid JP, Wilhelm M, Heidbuchel H, Völler H, Document reviewers. Comprehensive multicomponent cardiac rehabilitation in cardiac implantable electronic devices recipients: a consensus document from the European Association of Preventive Cardiology (EAPC; Secondary prevention and rehabilitation section) and European Hear. Europace. 2021 Feb 26; https://doi.org/10.1093/europace/euaa427

Iglesias JF, Heg D, Roffi M, Degrauwe S, Tüller D, Muller O, Brinkert M, Cook S, Weilenmann D, Kaiser C, Cuculi F, Valgimigli M, Jüni P, Windecker S, Pilgrim T. Five-year outcomes with biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients with acute coronary syndrome: A subgroup analysis of the BIOSCIENCE trial. Cardiovasc Revasc Med. 2021 Feb 25:S1553-8389(21)00092-0. https://doi.org/10.1016/j.carrev.2021.02.008

Rossi VA, Denegri A, Candreva A, Klingenberg R, Obeid S, Räber L, Gencer B, Mach F, Nanchen D, Rodondi N, Heg D, Windecker S, Buhmann J, Ruschitzka F, Lüscher TF, Matter CM. Prognostic value of inflammatory biomarkers and GRACE score for cardiac death and acute kidney injury after acute coronary syndromes. Eur Heart J Acute Cardiovasc Care. 2021 Feb 24; https://doi.org/10.1093/ehjacc/zuab003

Valgimigli M, Mehran R, Franzone A, da Costa BR, Baber U, Piccolo R, McFadden EP, Vranckx P, Angiolillo DJ, Leonardi S, Cao D, Dangas GD, Mehta SR, Serruys PW, Gibson CM, Steg GP, et al. Ticagrelor Monotherapy Versus Dual-Antiplatelet Therapy After PCI: An Individual Patient-Level Meta-Analysis. JACC Cardiovasc Interv. 2021 Feb 22;14(4):444–56. https://doi.org/10.1016/j.jcin.2020.11.046

Gragnano F, Branca M, Frigoli E, Leonardi S, Vranckx P, Di Maio D, Monda E, Fimiani L, Fioretti V, Chianese S, Esposito F, Franzese M, Scalise M, D’Angelo C, Scalise R, De Blasi G, Andò G, Esposito G, Calabrò P, Windecker S, Pedrazzini G, Valgimigli M, MATRIX Trial Investigators. Access-Site Crossover in Patients With Acute Coronary Syndrome Undergoing Invasive Management. JACC Cardiovasc Interv. 2021 Feb 22;14(4):361–73. https://doi.org/10.1016/j.jcin.2020.11.042

Ferini-Strambi L, Auer R, Bjorvatn B, Castronovo V, Franco O, Gabutti L, Galbiati A, Hajak G, Khatami R, Kitajima T, McEvoy D, Nissen C, Perlis M, Pevernagie DA, Randerath W, Riemann D, Rizzo G, Van Someren E, Vgontzas A, Barazzoni F, Bassetti C, European Sleep Foundation. Insomnia disorder: clinical and research challenges for the 21st century. Eur J Neurol. 2021 Feb 22; https://doi.org/10.1111/ene.14784

Albiński M, Saubade M, Benaim C, Menafoglio A, Meyer P, Capelli B, Perrin T, Trachsel L, Hagemeyer D, Casagrande D, Wilhelm M, Pirrello T, Albrecht S, Schmied C, Mivelaz Y, Tercier S, Baggish A, Gabus V. Impact of early sports specialisation on paediatric ECG. Scand J Med Sci Sports. 2021 Feb 22; https://doi.org/10.1111/sms.13942

Nozica N, Lam A, Goulouti E, Elchinova E, Spirito A, Branca M, Servatius H, Noti F, Seiler J, Baldinger SH, Haeberlin A, de Marchi SF, Asatryan B, Rodondi N, Donzé J, Aujesky D, Tanner H, Reichlin T, Jüni P, Roten L. The SilenT AtRial FIBrillation (STAR-FIB) study programme - design and rationale. Swiss Med Wkly. 2021 Feb 20;151:w20421. eCollection 2021 Feb 15. https://doi.org/10.4414/smw.2021.20421

Mesa-Vieira C, Grolimund J, von Känel R, Franco OH, Saner H. Psychosocial Risk Factors in Cardiac Rehabilitation: Time to Screen Beyond Anxiety and Depression. Glob Heart. 2021 Feb 19;16(1):16. http://doi.org/10.5334/gh.896

Muntané-Carol G, Taramasso M, Miura M, Gavazzoni M, Pozzoli A, Alessandrini H, Latib A, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, Sievert H, Denti P, Lubos E, Ludwig S, et al. Transcatheter Tricuspid Valve Intervention in Patients with Previous Left Valve Surgery. Can J Cardiol. 2021 Feb 19;https://doi.org/10.1016/j.cjca.2021.02.010

de Coulon E, Dellenbach C, Rohr S. Advancing mechanobiology by performing whole-cell patch clamp recording on mechanosensitive cells subjected simultaneously to dynamic stretch events. iScience. 2021 Feb 19;24(2):102041.https://doi.org/10.1016/j.isci.2021.102041

Brahimaj A, Ahmadizar F, Vernooij MW, Ikram MK, Ikram MA, van Walsum T, Dehghan A, Franco OH, Bos D, Kavousi M. Epicardial fat volume and the risk of cardiometabolic diseases among women and men from the general population.Eur J Prev Cardiol. 2021 Feb 18; https://doi.org/10.1093/eurjpc/zwaa026

Bernhard B, Gräni C. 18F-FDG PET/CT imaging in the workup of cardiac and pericardial masses. J Nucl Cardiol. 2021 Feb 18; https://doi.org/10.1007/s12350-021-02539-4

Pilgrim T, Rothenbühler M, Siontis GC, Kandzari DE, Iglesias JF, Asami M, Lefèvre T, Piccolo R, Koolen J, Saito S, Slagboom T, Muller O, Waksman R, Windecker S. Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients undergoing percutaneous coronary intervention: a meta-analysis of individual patient data from five randomized trials. Am Heart J. 2021 Feb 17; https://doi.org/10.1016/j.ahj.2021.02.009

Dejanovic GM, Asllanaj E, Gamba M, Raguindin PF, Itodo OA, Minder B, Bussler W, Metzger B, Muka T, Glisic M, Kern H. Phytochemical characterization of turnip greens (Brassica rapa ssp. rapa): A systematic review. PLoS One. 2021 Feb 17;16(2):e0247032. eCollection 2021. https://doi.org/10.1371/journal.pone.0247032

Ruperti-Repilado FJ, Thomet C, Schwerzmann M. [2020 ESC guidelines on treatment of adult congenital heart disease (ACHD)]. Herz. 2021 Feb;46(1):14-27. https://doi.org/10.1007/s00059-020-05003-0

Carrel TP, Czerny M. Commentary: Retrograde type A aortic dissection after TEVAR for type B aortic dissection- on the verge to oblivion? Semin Thorac Cardiovasc Surg. 2021 Feb 17; https://doi.org/10.1053/j.semtcvs.2021.01.047

Bona M, Wyss RK, Arnold M, Méndez-Carmona N, Sanz MN, Günsch D, Barile L, Carrel TP, Longnus SL. Cardiac Graft Assessment in the Era of Machine Perfusion: Current and Future Biomarkers. J Am Heart Assoc. 2021 Feb 16;10(4):e018966. https://doi.org/10.1161/JAHA.120.018966

Asatryan B, Yee L, Ben-Haim Y, Dobner S, Servatius H, Roten L, Tanner H, Crotti L, Skinner JR, Remme CA, Chevalier P, Medeiros-Domingo A, Behr ER, Reichlin T, Odening KE, Krahn AD. Sex-Related Differences in Cardiac Channelopathies: Implications for Clinical Practice. Circulation. 2021 Feb 16;143(7):739–52.https://doi.org/10.1161/CIRCULATIONAHA.120.048250

Rössler J, Baselga E, Davila V, Celis V, Diociaiuti A, El Hachem M, Mestre S, Haeberli D, Prokop A, Hanke C, Loichinger W, Quéré I, Baumgartner I, Niemeyer CM, Kapp FG. Severe adverse events during sirolimus “off-label” therapy for vascular anomalies. Pediatr Blood Cancer. 2021 Feb 13;e28936. https://doi.org/10.1002/pbc.28936

Dobner S, Gräni C, Hugi-Mayr B, Mihalj M, Rhyner D, Wieser M, Martinelli M, Hunziker L, Reineke D. Pump thrombosis and dynamic outflow graft compression: complications in left ventricular assist device therapy. ESC Heart Fail. 2021 Feb 10; https://doi.org/10.1002/ehf2.13244

Wernly B, Karami M, Engström AE, Windecker S, Hunziker L, Lüscher TF, Henriques JP, Ferrari MW, Binnebößel S, Masyuk M, Niederseer D, Abel P, Fuernau G, Franz M, Kelm M, Busch MC, Felix SB, Thiele H, Lauten A, Jung C. Impella versus extracorporal life support in cardiogenic shock: a propensity score adjusted analysis. ESC Heart Fail. 2021 Feb 9; https://doi.org/10.1002/ehf2.13200

González-Salvado V, Peña-Gil C, Lado-Baleato Ó, Cadarso-Suárez C, Prada-Ramallal G, Prescott E, Wilhelm M, Eser P, Iliou M-C, Zeymer U, Ardissino D, Bruins W, van der Velde AE, Van’t Hof AWJ, de Kluiver EP, Kolkman EK, Prins L, González Juanatey JR. Offering, participation and adherence to cardiac rehabilitation programmes in the elderly: a European comparison based on the EU-CaRE multicentre observational study. Eur J Prev Cardiol. 2021 Feb 9;https://doi.org/10.1093/eurjpc/zwaa104

Lyons O, Schmidli J. Preventing Stroke Due to Intervention in the Aortic Arch. Eur J Vasc Endovasc Surg. 2021 Feb 6;61(2):246–7. https://doi.org/10.1016/j.ejvs.2020.11.031

Praz F, Brugger N. Transcatheter tricuspid valve treatment: does annular reduction make a difference? EuroIntervention. 2021 Feb 5;16(15):e1213–4. https://doi.org/10.4244/EIJV16I15A219

Muntané-Carol G, Taramasso M, Miura M, Gavazzoni M, Pozzoli A, Alessandrini H, Latib A, Attinger-Toller A, Biasco L, Braun D, Brochet E, Connelly KA, de Bruijn S, Denti P, Deuschl F, Lubos E, et al. Transcatheter Tricuspid Valve Intervention in Patients With Right Ventricular Dysfunction or Pulmonary Hypertension: Insights From the TriValve Registry. Circ Cardiovasc Interv. 2021 Feb 5;CIRCINTERVENTIONS120009685. https://doi.org/10.1161/CIRCINTERVENTIONS.120.009685

Makaloski V, Widenka H, Schönhoff F, Spanos K, Wyss TR, Schmidli J. Efficacy and safety of heparinization before deployment of endograft for blunt traumatic aortic injury in severely injured patients. Ann Vasc Surg. 2021 Feb 5;https://doi.org/10.1016/j.avsg.2021.01.096

Okuno T, Corpataux N, Spano G, Gräni C, Heg D, Brugger N, Lanz J, Praz F, Stortecky S, Siontis GCM, Windecker S, Pilgrim T. True-severe Stenosis 1 in Paradoxical Low-flow Low-gradient Aortic Stenosis: Outcomes after Transcatheter Aortic Valve Replacement. Eur Heart J Qual Care Clin Outcomes. 2021 Feb 4; https://doi.org/10.1093/ehjqcco/qcab010

Makaloski V, Tsilimparis N, Panuccio G, Spanos K, Wyss TR, Rohlffs F, Debus ES, Kölbel T. Perioperative outcome of fenestrated and branched stent grafting after previous open or endovascular abdominal aortic repair. Ann Vasc Surg. 2021 Feb 4; https://doi.org/10.1016/j.avsg.2020.12.047

Leonardi S, Branca M, Franzone A, McFadden E, Piccolo R, Jüni P, Vranckx P, Steg PG, Serruys PW, Benit E, Liebetrau C, Janssens L, Ferrario M, Zurakowski A, Diletti R, Dominici M, et al. Comparison of Investigator-Reported and Clinical Event Committee-Adjudicated Outcome Events in GLASSY. Circ Cardiovasc Qual Outcomes. 2021 Feb 4;14(2):e006581. https://doi.org/10.1161/CIRCOUTCOMES.120.006581

Chichareon P, van Klaveren D, Modolo R, Kogame N, Takahashi K, Chang C-C, Tomaniak M, Yuan J, Xie L, Song Y, Qiao S, Yang Y, Guan C, Zurakowski A, van Geuns R-J, Sabate M, et al. Predicting 2-year all-cause mortality after contemporary PCI: Updating the logistic clinical SYNTAX score. Catheter Cardiovasc Interv. 2021 Feb 4;https://doi.org/10.1002/ccd.29490

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